Figure 7

Survival of yej gene deletion mutants and B. melitensis NI in mice.
Ten mice were inoculated with each strain at a dose of 106 CFU/mouse. Five mice/group were euthanized at 1 and 3 weeks post-inoculation and the virulence of each strain was determined based on the number of CFUs recovered from the spleen, which was expressed as the mean ± SD (n = 5) of individual log10 CFU/spleen values. Significant differences between every mutant and parental strain are indicated by an asterisk (P < 0.05).