Figure 4

Cytokine-producing T cells in the LPL of colon in IL-21RKO mice with DSS-induced colitis.

(A) The proportions and absolute numbers of IFN-γ⁺CD4⁺, IFN-γ⁺CD8⁺, IL-4⁺CD4⁺ T in LPL of colon; (B) The percentage of CD44⁺IFN-γ⁺ in CD4⁺ or CD8⁺ T cells in LPL of colon; (C) The proportion and absolute number of IL-5⁺CD4⁺ T cells in LPL of colon; (D) The proportion and absolute number of IL-17A⁺CD4⁺ T cells in LPL of colon. Data indicate mean ± SD of 3 mice of each group obtained from a representative of three independent experiments. Statistically significant differences are shown (*P < 0.05 or **P < 0.01).