Figure 8 | Scientific Reports

Figure 8

From: IL-21/IL-21R signaling suppresses intestinal inflammation induced by DSS through regulation of Th responses in lamina propria in mice

Figure 8

rIL-21-treatment improved intestinal inflammation induced by DSS in C57BL/6 mice.

(A) IL-21 production by LP-T cell of colon from control or rIL-21-treated mice was analyzed on day 2, 4 and 6 after DSS-administration. (B) The percentage and absolute number of IFN-γ-, IL-17A-, IL-4- or IL-10-producing CD4+ LP-T cells from colon of control or rIL-21-treated mice were analyzed by cytokine FACS on day 6 after DSS-treatment. Data indicate mean ± SD of 3 mice of each group obtained from a representative of tow independent experiments. Statistically significant differences are shown (*P < 0.05 or **P < 0.01).

Back to article page