Figure 1: Biofunctional microcavity arrays.

(A) Confocal laser scanning microscopy (CLSM) image of a PDMS microcavity array (Ø: 40 μm) functionalized with fluorophore-labeled FN (green) (left). Scale bar: 50 μm. Surface chemistry used for covalent immobilization of FN (right). (B) Schematic representation of the hydrogel micropatterning concept. (C) 3D image of polystyrene pillar microarray (Ø: 15 μm, h: 10 μm) derived by SAMIM and imaged by multi-pinhole microscopy. (D) CLSM images of sPEG-heparin hydrogel microarrays of hexagonal packed cavities with diameters of 15 μm (left) or 40 μm (right) labeled with Alexa633 fluorophore (red). Scale bars: 40 μm.