Figure 4: STAT5 is a downstream target of GRAMD1A. | Scientific Reports

Figure 4: STAT5 is a downstream target of GRAMD1A.

From: GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth through STAT5

Figure 4

(a) Analysis of the correlation between GRAMD1A levels and STAT5 levels using GSEA. (b) Quantitative real-time PCR assay for the mRNA levels of STAT5, CyclinD1, Bcl-2, c-jun and c-Myc after GRAMD1A overexpression or knockdown. (c) Luciferase activity assay was used to determine whether GRAMD1A could regulate the transcriptional activity of STAT5. Data are expressed as mean ± SEM. *p < 0.05.

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