Table 3 Results of CRP haplotype analysis according to the presence/absence of CV events or subclinical atherosclerosis in RA patients.

From: Influence of elevated-CRP level-related polymorphisms in non-rheumatic Caucasians on the risk of subclinical atherosclerosis and cardiovascular disease in rheumatoid arthritis

Haplotypes

Presence/absence of CV events

Presence/absence of carotid plaques

cIMT

rs1417938

rs1800947

rs1205

P*

HR [95% CI]*

P**

OR [95% CI]**

P***

T

C

C

—

1 (reference)

—

1 (reference)

—

A

C

C

0.21

1.19 [0.90–1.60]

0.21

1.14 [0.92–1.41]

0.54

T

C

T

0.37

0.86 [0.62–1.19]

0.78

0.95 [0.64–1.39]

0.41

A

C

T

0.72

0.93 [0.62–1.39]

0.60

1.15 [0.69–1.89]

0.60

  1. CV: cardiovascular; RA: rheumatoid arthritis; cIMT: carotid intima-media thickness; HR: hazard ratios; CI: confidence interval; OR: odds ratio. *Adjustment for gender, follow-up time, age at RA diagnosis and traditional CV risk factors by Cox regression. **Adjustment for gender, follow-up time, age at the time of ultrasonography study and traditional CV risk factors by logistic regression. ***Adjustment for gender, follow-up time, age at the time of ultrasonography study and traditional CV risk factors using analysis of covariance (ANCOVA).
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