Table 2 Clinical data of patients with IgA nephropathy (non-crescentic IgA-GN (IgA-GN) and cellular-crescentic IgA-GN (crescentic IgA-GN)) and controls. If no unit is given data are presented as total count, otherwise as median (25th/75th percentile).

From: Comparison of different normalization strategies for the analysis of glomerular microRNAs in IgA nephropathy

 

IgA-GN; n = 5

Crescentic-IgA-GN; n = 5

Controls; n = 5

Female

2

3

4

Age at biopsy

47.0 (37.0/51.0)

46.0 (17.0/65.0)

37.0 (24.0/55.0)

Crescents per total glomeruli count (%)

0 (0/0)

44.4 (36.6/46.2)

0 (0/0)

Global glomerulosclerosis per total glomeruli count (%)

5.9 (5.9/6.3)

9.8 (0/10)

0 (0/0)

Arterial hypertension WHO-Grade

 0

3

2

3

 1

1

2

1

 2

1

0

0

 3

0

1

0

 n.d.

0

0

1

Proteinuria

 normal

0

0

2

 <3.5 g/day

5

3

3

 >3.5 g/day

0

2

0

 n.d.

0

0

0

Microhematuria

5

4

2

Macrohematuria

1

1

0

Haemoglobin (g/dl)

13.1 (11.1/15.4)

10.9 (10.8/12.7)

12.5 (9.1/14.1)

Leukocytes (103/μl)

6.8 (5.6/7.4)

8.1 (7.7/8.8)

8.8 (5.7/11.3)

Thrombocytes (103/μl)

237 (192/257)

360 (292/401)

245 (166/484)

Serum-Creatinine (μmol/l)

84 (68/232)

107 (79/450)

273 (129/465)

eGFR MDRD (ml/min) (Schwartz if age <18 years)

88.8 (42.2/96.0)

54.7 (22.1/95.5)

18.0 (15.8/40.8)

  1. Although serum creatinine of controls was higher than those in patients with IgA nephropathy, there were no significant differences. Furthermore, there were no significant differences for eGFR (Steel-Dwass test).