Figure 3: Immunohistochemical staining for CD68⁺ macrophages in the lungs of PbANKA-infected mice with or without α-lactose treatment.

(a) Immunohistochemical staining of CD68⁺ macrophages (green arrows) in the lungs of uninfected mice, uninfected mice treated with α-lactose, malarial mice, and malarial mice treated with α-lactose on days 7 p.i. Original magnification ×1,000. (b) Morphometric analysis of lung tissues. Shown are CD68⁺ macrophages per square millimeter. Data are presented as means ± SD; experiments were performed with three mice per group. ***P < 0.001, malarial mice on 7 days p.i. and malarial mice treated with α-lactose on 7 days p.i. vs. naive group; ξξξ, P < 0.001, malarial mice treated with α-lactose on 7 days p.i. vs. malarial mice on 7 days p.i.