Table 1 Differentially expressed miRNAs in pre-operative meningioma patients compared to healthy controls from the Changzhou cohort.
From: A serum 6-miRNA panel as a novel non-invasive biomarker for meningioma
miRNA | Training set | Validation set | Training + Validation | Result | |||
---|---|---|---|---|---|---|---|
Mean fold | p-value | Mean fold | p-value | Mean fold | p-value | ||
miR-106a-5p | 2.829 | 5.24 × 10−4 | 3.173 | 2.42 × 10−8 | 3.058 | 4.52 × 10−11 | significant |
miR-219-5p | 2.119 | 7.80 × 10−3 | 2.443 | 9.41 × 10−6 | 2.334 | 2.21 × 10−7 | significant |
miR-375 | 2.382 | 1.23 × 10−2 | 2.494 | 4.75 × 10−2 | 2.457 | 6.36 × 10−3 | significant |
miR-409-3p | 2.133 | 7.97 × 10−4 | 2.868 | 2.37 × 10−6 | 2.662 | 4.14 × 10−8 | significant |
miR-197-3p | 0.321 | 5.95 × 10−6 | 0.309 | 3.73 × 10−11 | 0.313 | 8.38 × 10−9 | significant |
miR-224-5p | 0.430 | 2.06 × 10−3 | 0.357 | 5.90 × 10−5 | 0.377 | 9.39 × 10−7 | significant |
miR-19b-3p | 2.135 | 3.53 × 10−3 | 1.832 | 1.85 × 10−2 |  |  | not significant |
miR-107 | 0.403 | 1.87 × 10−4 | 0.651 | 6.34 × 10−1 |  |  | not significant |