Figure 1 | Scientific Reports

Figure 1

From: TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression

Figure 1

Generation of Trf2tag/tag mice.

(A) Schematic representation of WT and modified Trf2 alleles with those of the partially overlapping Slc2a12 gene. Exons (E) are indicated along with the Trf2 stop codon, the location of the Tap-Tag and the FRT sites. (B) Immunoblot on protein extracts from testis of WT and Trf2tag/tag testes. Molecular mass markers are indicated on the left of the panel. (C) Hoechst staining of histological sections from mice of the indicated genotypes. RS shows round spermatids with a prominent chromocenter, PS shows pachytene spermatocytes and ES elongate spermatids.

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