Figure 4 | Scientific Reports

Figure 4

From: TRF2 is recruited to the pre-initiation complex as a testis-specific subunit of TFIIA/ALF to promote haploid cell gene expression

Figure 4

Trf2 occupies active promoters.

(A) UCSC screen shot of ChIP-seq for the indicated factors over a 3-megabase region illustrating the colocalisation of Trf2, Tbp, Pol II and Taf7l at active promoters. (B) Read density clustering showing, colocalisation of Trf2 with Pol II at a subset of promoters active in testis and co-localisation and proportionality of Trf2, Tbp and Taf7l occupancy at 6000 Trf2 bound sites and 6000 Tbp bound sites. (C) Meta-profiles of the ChIP-seq data for the indicated factors in Trf2tag/tag and Trf2−/− testis.

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