Figure 1: Effect of SERMs on free cholesterol and nonpolar lipid distribution in THP-1 macrophages. | Scientific Reports

Figure 1: Effect of SERMs on free cholesterol and nonpolar lipid distribution in THP-1 macrophages.

From: Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport

Figure 1

Cells were treated with AcLDL and vehicle (Control) or 10 μM tamoxifen (TAM), raloxifene (RAL) or toremifene (TOR). (a) Fluorescence microscopy of stainings with filipin for free cholesterol. (b) Confocal microscopy of costainings with filipin (blue) and Bodipy (green) for nonpolar lipids. Photographs are representative examples from three independent experiments.

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