Figure 3: Effect of SERMs on ABCA1, ABCG1 and SR-BI protein expression in THP-1 macrophages.

(a) Cells were incubated in the absence or presence of AcLDL and the indicated concentrations of tamoxifen (TAM) or T0901317 (T0, 1 μM). (b) Cells were treated with AcLDL and vehicle (Con, control) or tamoxifen (TAM), raloxifene (RAL) or toremifene (TOR) (10 μM) and in the absence or presence of T0901317 (1 μM).