Figure 4
From: Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide
Role of HHI in IAPP gelation.
(a) Rheological properties of a 4 μM IAPP solution in H2O in presence of 4 μM liposomes (7 DOPC:3 DOPG) were assessed at 25 °C with a controlled displacement of 5 × 10−3 rads and a frequency of 0.5 Hz. Dynamic moduli G’ and G” as a function of time, with the inset showing G’ and G” as a function of angular frequency ω. (b) The lag time for moduli increase, rate of increase and plateau reached are depicted. The mean of five independent assays is shown. Error bars represent ± SEM. **p < 0.0006. lipo.: liposomes.
