Figure 5: Young human Alu elements prefer mCW. | Scientific Reports

Figure 5: Young human Alu elements prefer mCW.

From: Mammalian non-CG methylations are conserved and cell-type specific and may have been involved in the evolution of transposon elements

Figure 5

Profiles of mCW across the sub-groups of human Alu elements from 500 bp upstream to 500 bp downstream in brain neuron, ES and oocyte. The mCW levels are shown for the sense strand (red) and antisense strand (green) separately. AluJo is the most ancient, and AluY is the youngest Alu elements. Yellow blocks mark the loci of Alu elements, where mCW levels increase with the evolution of Alu elements. The corresponding sequence mutations are shown below the profiles, and the nucleotides at the mutated positions are marked in red.

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