Figure 4

Determination of enzyme activity of AroK and AroL in vitro.
(a) The enzyme activity of AroK; (b) The enzyme activity of AroL. The activities of the purified shikimate kinase was determined by coupling the release of ADP from the shikimate kinase-catalyzed reaction to the oxidation of NADH using pyruvate kinase and lactate dehydrogenase as coupling enzymes. Shikimate-dependent oxidation of NADH was monitored at A340 (ε = 6,200 M−1cm−1) at 25 °C. The data are from three experimental replicates.