Table 1 Reaction optimization of one pot Pictet Spengler-Oxidative ring contraction of tryptamine to furnish spiro[pyrrolidine-3, 3´-oxindole].

From: Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification

  1. aIsolated yield.
  2. bn. r.: no reaction.
  3. cTetrabutyl ammonium bromide (TBAB).
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