Table 5 Factors associated with SVR identified by multivariate analyses in 156 chronic hepatitis C subjects receiving pegylated interferon plus ribavirin therapy.

From: Association of SCARB1 Gene Polymorphisms with Virological Response in Chronic Hepatitis C Patients Receiving Pegylated Interferon plus Ribavirin Therapy

Clinical factors

OR(95% CI)

P value

Age, year

0.95(0.91–1.004)

0.071

Sex, (Male vs. Female)

5.09(2.09–12.4)

<0.001

HCV RNA Log10, IU/mL

0.39(0.22–0.68)

0.001

ALT,U/L

1.003(0.999–1.007)

0.166

PLT, K/ul

1.003(0.99–1.01)

0.512

rs10846744 genotype, (GG genotype = 1)

0.32(0.11–0.95)

0.039

  1. NOTE. This table showed the associations of clinical factors and SVR. Use SVR as the dependent variable and age in 1-year increment, sex, serum HCV RNA, ALT, platelet count and rs10846744 genotype as independent variables. Serum HCV RNA level is Log 10 transformed.
  2. rs10846744 GG genotype is significantly associated with a lower SVR rate in multivariate analyses.
  3. Abbreviations: ALT, alanine aminotransferase; PLT, platelet count.
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