Figure 3: Phenotypic analysis of MAIT cells from tuberculous pleural effusions and peripheral blood. | Scientific Reports

Figure 3: Phenotypic analysis of MAIT cells from tuberculous pleural effusions and peripheral blood.

From: Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling

Figure 3

(A) Frequency of CD8α+ MAIT cells in peripheral blood of healthy controls (HC/PB) and patients with TB (TB/PB), and in tuberculous pleural effusions (PE). (B) Frequency of CD4−CD8α− (DN) MAIT cells. (C) Representative flow plots showing expression of CD45RO in MAIT cells from peripheral blood (PB) and tuberculous pleural effusion (PE) in the absence of antigen stimulation. (D) Frequencies of CD45RO+ MAIT cells. (E) Representative flow plots showing expression of CD62L in MAIT cells in the absence of antigen stimulation. (F) Frequencies of CD62L+ MAIT cells. (G–I) Frequencies of CD26+ (G), CD27+ (H), CD39+ (I) MAIT cells in peripheral blood of patients with TB (PB) and in tuberculous pleural effusions (PE) respectively. Horizontal bars in the scatter plots indicate medians. Kruskal-Wallis test was used for statistical analysis among groups in Fig. 3A,B. The nonparametric Mann-Whitney test was used for statistical analysis between groups in Fig. 3D,F,G–I.

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