Figure 7: IL-2 and IL-12 receptor expression on MAIT cells from peripheral blood and tuberculous pleural effusions. | Scientific Reports

Figure 7: IL-2 and IL-12 receptor expression on MAIT cells from peripheral blood and tuberculous pleural effusions.

From: Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling

Figure 7

(A) Representative flow plots showing γc (CD132) isotype control antibody staining of MAIT cells from peripheral blood (PB) and tuberculous pleural effusion (PE). (B) Representative flow plots showing expression of γc receptor (CD132) on MAIT cells in the absent of antigen stimulation. (C) Representative flow plots showing expression of γc receptor (CD132) on Mtb-stimulated MAIT cells from peripheral blood (PB) and tuberculous pleural effusion (PE). (D–E) MAIT cells from tuberculous pleural effusions exhibited significantly higher expression of γc receptor (CD132) than those from peripheral blood both in the absent of antigen stimulation (D) and after Mtb stimulation (E). (F–G) The expression of IL-2Rβ on MAIT cells in the absent of antigen stimulation (F) or after Mtb stimulation (G). (H–I) The expression of IL-2Rα on MAIT cells in the absent of antigen stimulation (H) or after Mtb stimulation (I). (J) The expression of IL-12Rβ1 on MAIT cells in the absent of antigen stimulation. Horizontal bars in the scatter plots indicate medians. The nonparametric Mann-Whitney test was used for statistical analysis between groups.

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