Figure 1
From: SOX9-regulated cell plasticity in colorectal metastasis is attenuated by rapamycin
High levels of SOX9 correlate with CR-CSCs.
(A) Higher expression of stem cell markers in SW620 than in SW480 cells (n ≥ 3). (B) SOX9 mRNA expression relative to GAPDH in normal and tumoral colonic paired human samples and in SW480 and SW620 cell lines. (C) Higher SOX9 protein expression and phospho-SOX9 (S181) in SW620 cells than in SW480 cells. (D) Number of tumorspheres derived from SW480 and SW620 cells (n = 6). (E) SOX9 and BMI1 protein expression in tumorspheres and in parental SW480 and SW620 cells (n = 3). (F) Stem cell marker mRNA expression levels in tumorspheres relative to the corresponding parental cells (n ≥ 3).
