Table 4 The GIDs target information.

From: Systems Pharmacology Dissection of the Integrated Treatment for Cardiovascular and Gastrointestinal Disorders by Traditional Chinese Medicine

Gene name

Protein name

Degree

ESR1

Estrogen Receptor

18

NR3C1

Glucocorticoid receptor

12

AR

Androgen Receptor

8

PlA2G2A

Phospholipase A2 group IIA

8

CYP2A6

Cytochrome P450 2A6

7

CYP1B1

Cytochrome P450 1B1

6

GLO1

Glyoxalase I

4

ACHE

Acetylcholinesterase

3

NOS1

Nitric Oxide Synthase, brain

3

HSD17B2

Estradiol 17-beta-dehydrogenase 2

2

PLK2

Polo-Like Kinase 2

2

CCNE2

Cyclin-dependent kinase 2

2

MMP9

Matrix metalloproteinase 9

2

CYP2C9

Cytochrome P450 2C9

2

SCD

Acyl-CoA desaturase

1

COX-2

Cyclooxygenase-2

1

HRH3

Histamine H3 Receptor

1

MGAM

Maltase-glucoamylase

1

SELP

P-selectin

1

HIF1AN

Hypoxia-inducible factor 1-alpha inhibitor

1

CA9

Carbonic anhydrase 9

1

CASP9

Caspase-9

1

ADRA1B

Alpha-1b adrenergic receptor

1

TERT

Telomerase reverse transcriptase

1