Table 5 The CVDs target information.

Adenylate cyclase type V

47

Cytochrome P450 2A5

35

Glucocorticoid receptor

20

5-hydroxytryptamine receptor 2A

18

Estrogen Receptor

18

Aldehyde dehydrogenase

15

Cytochrome P450 1A1

13

Glucocorticoid receptor

12

Phosphodiesterase 2A

12

Vitamin D receptor

9

Aldose reductase

9

Androgen Receptor

8

5-Lipoxygenase

8

glucose-6-phosphate 1-dehydrogenase isoform b

8

Phospholipase A2 group IIA

8

Retinoic acid receptor alpha

8

Cytochrome P450 2A6

7

Melatonin receptor 1A

5

Arachidonate 12-lipoxygenase

4

Glyoxalase I

4

Acetylcholinesterase

3

Serotonin 5a receptor

3

Leukotriene A4 Hydrolase

3

Serotonin Transporter

3

v-rel reticuloendotheliosis viral oncogene homolog A isoform 1

3

Adenosine A1 receptor

3

5-Lipoxygenase

2

Polo-Like Kinase 2

2

Translocator protein

2

NADPH oxidase 4

2

G protein-coupled receptor 35

2

Adenosine Receptor A2A

2

Matrix metalloproteinase 9

2

Adenosine receptor A3

2

Alpha-2b adrenergic receptor

2

Matrix metalloproteinase-3

2

Fatty acid binding protein adipocyte

1

Secreted frizzled-related protein 1

1

Phospholipase A2

1

Vasopressin V2 Receptor

1

Interleukin-8 receptor A

1

Myeloperoxidase

1

Sorbitol dehydrogenase

1

Coagulation factor III/VII

1

Poly [ADP-ribose] polymerase-1

1

Beta-1 adrenergic receptor

1