Figure 1: Passive exposure to 3830 m is associated with increased oxidative stress and optic nerve sheath diameter. | Scientific Reports

Figure 1: Passive exposure to 3830 m is associated with increased oxidative stress and optic nerve sheath diameter.

From: Oxidative stress response to acute hypobaric hypoxia and its association with indirect measurement of increased intracranial pressure: a field study

Figure 1

Time course of mean reactive oxygen species production rate (ROS, μmol∙min−1) (A), total antioxidant capacity (TAC, mM Trolox) (B), thiobarbituric acid-reactive substances (TBARS, μM) (C), 8-isoprostanes (8-isoPGF2α, ng∙mg−1 creatinine) (D), optic nerve sheath diameter (ONSD, mm) (E) and oxygen saturation (SpO2, %) (F) at baseline (BL, 262 m) and after 9, 24, and 72 h at 3830 m. Vertical bars represent standard deviation. P-values refer to different time points compared to baseline and are represented with symbols (*0.01 ≤ p < 0.05; #0.001 ≤ p < 0.01; §p < 0.001).

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