Figure 5
In vitro anti-metastasis research of FLP/PEDF.
Mean ± SD, n = 3. (A) Adhesion assay. FLP/PEDF significantly decreased HeLa cells adhesive rate at all the determined time points compared to control, PLP/PEDF, FLP/PAAV2 and PLP/PAAV2. *p < 0.05. (B) Representative images of migrated HeLa cells derived from invasion assay and relative metastasis rates of HeLa cells. FLP/PEDF observably restrain HeLa cells invasion. ***p < 0.001, all the nano-lipoplexes versus control. △△p < 0.01. ###p < 0.001. (C) Representative images of scratch assay and fusion rates of HeLa cells. *p < 0.05, PLP/PAAV2 versus control. ***p < 0.001, the other three nano-lipoplexes versus control. ##p < 0.01. △△△p < 0.001.
