Figure 6 | Scientific Reports

Figure 6

From: Promising Nanocarriers for PEDF Gene Targeting Delivery to Cervical Cancer Cells Mediated by the Over-expressing FRα

Figure 6

In vivo anti-tumor effect of FLP/PEDF by comparison with control, PLP/PAAV2, FLP/PAAV2, PLP/PEDF.

The abdominal metastatic tumor model of cervical cancer was established by injecting HeLa cells into the abdomen and these nude mice were treated by intraperitoneal injection. FLP/PEDF exhibited a superior anti-tumor effect. Mean ± SD, n = 5. ***p < 0.001, all the nano-lipoplexes versus control. (A) Photographs of cervical tumor tissues. (B) Weight of tumors. △△△p < 0.001. (C) Amount of tumor nodules. (D) Volume of ascites. △△p < 0.01.

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