Figure 8: The conditioned medium of cardiac fibroblasts (CFs) treated with β1-AA increased early apoptosis in cardiomyocytes. | Scientific Reports

Figure 8: The conditioned medium of cardiac fibroblasts (CFs) treated with β1-AA increased early apoptosis in cardiomyocytes.

From: Proliferation in cardiac fibroblasts induced by β1-adrenoceptor autoantibody and the underlying mechanisms

Figure 8

(A) The conditioned medium of CFs stimulated with β1-AA for 24 h after neutralizing β1-AA using β1-AR-EC II were added to neonatal rat cardiomyocytes for 24 h, cell early apoptosis was evaluated by Annexin V/PI apoptosis kit. Data shown here are representative of one of three individual experiments with similar results. (B) The supernatant of CFs stimulated by β1-AA for 24 h promoted the early apoptosis of H9c2 cell lines in 24 h. **P < 0.01 vs. conditional medium of CFs treated with IgG group. #P < 0.01 vs. conditional medium of CFs treated with β1-AA group.

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