Figure 5
From: Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach
Ingenuity pathway analysis performed on male versus female fold change values (M/F FC) of both transcriptomic and metabolomic data.
Top dysregulated molecular pathways represented on bar chart (A) and heatmap (B). Molecular functions that are specifically activated in males and females (Supplementary Table S6) are indicated in blue and red, respectively. Examples of significant molecular networks related to RNA post-translational modification (C) and lipid metabolism (D) processes (score = 38 and 28). Relative up-regulation of transcripts and metabolites in males or in females are indicated in blue and red, respectively.
