Figure 6: Effects of treatment with decitabine, ionizing radiation (IR), or their combination on cytolytic activity of NK cells against target tumor cells.

NK cells were co-cultured with A549, HCT-116, and HepG2 cells at various ratios for 4 h, and cytotoxicity assay was performed by flow cytometry. Results are expressed as average NK cell-induced cytotoxicity ± SD against A549, HCT-116, and HepG2 cells. Experiments were independently performed from five healthy donors. The assay was performed in triplicated each donor. The statistical significance was determined using a one-way ANOVA.