Table 2 General features of the first 10 Drp53 BSs: gene symbol, motif location, position with respect to the gene TSS, presence within repeat element and gene functional details are reported.
# | Gene | Chr | Pattern start | Pattern end | Position vs TSS | Overlap within repeat | Note |
---|---|---|---|---|---|---|---|
1 | hspa8 | 10 | 30761068 | 30761101 | exon9 | No | Belonging to human P53 network. |
2 | stat3 | 3 | 16723031 | 16723052 | intron22–23 | No | High rank by both prioritization tools, but pattern is not located in canonical regions (within the 4–5th intron). |
3 | axin1 | 3 | 43009715 | 43009734 | intron5–6 | Yes hAT-N54_DR | High rank by both prioritization tools; pattern in repeat element |
4 | vcp | 5 | 43134399 | 43134429 | intron8–9 | Yes hAT-N52_DR | High rank by both prioritization tools; Pattern partially in repeat element |
5 | runx1 | 1 | 1067563 | 1067595 | intron2–3 | No | High rank by both prioritization tools; Multiple patterns in the region |
6 | dnajc9 | 12 | 10255976 | 10256007 | upstream | No | Plausible pattern position with respect to TSS; expressed in central nervous system. |
7 | traf4a | 15 | 14555737 | 14555756 | 5′UTR | No | Plausible pattern position with respect to TSS; expressed in central nervous system. |
8 | necab2 | 18 | 21197526 | 21197546 | upstream | No | Plausible pattern position with respect to TSS ; expressed in central nervous system. |
9 | ttyh2l | 3 | 52217686 | 52217707 | upstream | No | Plausible pattern position with respect to TSS; expressed in neural tube. |
10 | col4a5 | 7 | 52559622 | 52559647 | upstream | No | Plausible pattern position with respect to TSS; expressed in diencephalon. |