Table 1 Linear regression analysis of microbiota before and after HF feeding to body weight gains and body weights of DIO mice.

From: High fat diet drives obesity regardless the composition of gut microbiota in mice

 

Microbiota before HF feeding

Microbiota after 10 wks HF feeding

1st wk body weight gain on HF

Total body weight gain on HF

Final body weight

P value

R2

P value

R2

P value

R2

InvSimpson

0.0638

0.08982

0.5237

0.01108

0.0446

0.1074

Shannon

0.0257

0.1274

0.2742

0.03222

0.0301

0.1240

Chao1

0.0497

0.1002

0.1723

0.04974

0.3055

0.02914

F/B

0.2457

0.03527

0.9035

0.0004

0.487

0.0128

  1. Relationships of microbiota diversity with 1st week weight gain, total weight gain and final body weight of conventional mice on a HF diet. Linear regression analysis was used to calculate the three alpha diversity indices, InvSimpson (inverse Simpson), Shannon and Chao 1, and microbiota F/B ratios and different weight gain parameter. Goodness of fit (R2) and p-value of correlation are shown.