Figure 3
From: Myostatin inhibition therapy for insulin-deficient type 1 diabetes
MyoLn/Ln diabetic animals have greater insulin sensitivity to bolus insulin injection and increased expression of key glucose transporters.
(A) Blood glucose measures following insulin tolerance test. Broken line, black circle – diabetic; Unbroken line, white circle – MyoLn/Ln diabetic. AUC – area under the curve. N = 5–6. Unpaired t-test. *Indicates p < 0.05. (B) Plasma insulin measurement. N = 4. White bar – non-diabetic, black bar – diabetic (C) Glut-1 protein expression. N = 3–4. Two-way ANOVA with Bonferroni post-hoc test. *Indicates p < 0.05. (D) Glut-4 protein expression. N = 4.
