Table 4 Comparison of neurocognitive test scores between parent and control groups.

From: Performance of Verbal Fluency as an Endophenotype in Patients with Familial versus Sporadic Schizophrenia and Their Parents

 

FS parent

SS parent

Control

ANOVA

Tukey’s HSD test

WIS-RC

 Verbal IQ

96.15 (14.90)

101.33 (15.60)

104.42 (16.74)

F = 9.10**

FR-control p < 0.001**

SR-control p = 0.13

FR-SR p = 0.02*

 Performance IQ

90.82 (13.47)

92.09 (14.25)

93.88 (14.26)

F = 1.74

FR-control p = 0.42

SR-control p = 0.18

FR-SR p = 0.73

 IQ

93.18 (13.71)

96.89 (14.47)

99.69 (14.78)

F = 6.94**

FR-control p < 0.001**

SR-control p = 0.13

FR-SR p = 0.08

WMS-RC

 Immediate logical memory

6.99 (3.35)

7.60 (3.52)

9.65 (3.48)

F = 25.89**

FR-control p < 0.001**

SR-control p < 0.001**

FR-SR p = 0.30

 Delayed logical memory

4.73 (3.57)

5.22 (3.38)

7.32 (3.53)

F = 25.60**

FR-control p < 0.001**

SR-control p < 0.001**

FR-SR p = 0.47

 VFT, valid words

16.82 (3.90)

18.25 (3.60)

18.38 (4.51)

F = 5.73**

FR-control p = 0.004**

SR-control p = 0.95

FR-SR p = 0.009**

Trail Test

 TMA: time to completion

53.06 (14.97)

52.85 (14.13)

51.48 (13.14)

F = 0.64

FR-control p = 0.62

SR-control p = 0.59

FR-SR p = 0.99

 TMB-M: time to completion

86.89 (34.24)

82.83 (23.74)

76.43 (19.63)

F = 6.65**

FR-control p = 0.002**

SR-control p = 0.03*

FR-SR p = 0.36

WCST -M

 Perseverative errors

9.57 (7.18)

8.21 (5.91)

4.58 (3.14)

F = 36.32**

FR-control p < 0.001**

SR-control p < 0.001**

FR-SR p = 0.09

 Categories

3.70 (1.82)

4.11 (1.68)

4.81 (1.22)

F = 19.60**

FR-control p < 0.001**

SR-control p < 0.001**

FR-SR p = 0.07

  1. FS parent (FR), familial schizophrenia parent; SS parent (SR), sporadic schizophrenia parent; Mean (Standard Deviation, SD); *p < 0.05, **p < 0.005.
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