Figure 3
From: Glucosamine and N-acetyl glucosamine as new CEST MRI agents for molecular imaging of tumors
Images of CEST MRI kinetic measurements in mice bearing MCF7 tumors (human cancer cells) at different times following IV (a–d) and PO (e–h) administration of GlcN, 1.0 g/kg (B1 = 2.4 μT, B0 = 7 T). (a,e) A T2-weighted image before administration of the agent (the conventional image). (b,f) A CEST image before administration of the agent (10.4% and 7.8% CEST in the whole tumor, respectively). (c,g) A CEST image 48 and 41 mins after administration of the agent (14.6% and 13.4% CEST in the whole tumor, respectively). (d,h) The time series of the % CEST achieved in the tumor.
