Figure 1

Doxycycline administration in apoE−/− mice.
(A) Body weight in control and doxycycline-treated apoE−/− mice on high fat diet, measured during the 3 month-period of drug administration. n = 10 in each group. (B) Blood doxycycline concentrations measured by high performance liquid chromatography in doxycycline-treated and control animals. n = 2 in each group.