Table 4 Logistic regression analysis of predictors for in-hospital mortality among 105 patients with CnsKP isolates.

From: High minimum inhibitory concentration of imipenem as a predictor of fatal outcome in patients with carbapenem non-susceptible Klebsiella pneumoniae

Variable

Univariate analysis

Multivariable analysis

OR (95% CI)

p

OR (95% CI)

p

Infection

6.90 (2.13–22.36)

0.001

  

Nosocomial-acquired isolates

2.80 (0.93–8.38)

0.066

  

Imipenem MIC ≥4

5.80 (1.58–21.27)

0.008

  

Imipenem MIC ≥8

2.21 (0.98–4.96)

0.055

  

Imipenem MIC ≥16

3.51 (1.56–7.92)

0.002

3.17 (1.11–9.05)

0.032

Diabetes mellitus

2.06 (0.87–4.14)

0.108

  

Chronic renal failure

2.74 (1.19–6.30)

0.018

  

Charlson Comorbidity Index

1.31 (1.11–1.56)

0.002

  

Indwelling central venous catheter

2.93 (1.29–6.68)

0.010

  

Nasogastric tube

8.52 (2.36–30.77)

0.001

6.19 (1.07–9.05)

0.042

Mechanically ventilated at isolation

4.12 (1.68–10.06)

0.002

  

Renal dialysis at isolation

2.14 (0.80–5.73)

0.131

  

APACHE II score

1.17 (1.10–1.25)

<0.001

1.13 (1.06–1.21)

<0.001

  1. Data are the number (%) unless specified otherwise.
  2. APACHE, Acute Physiology and Chronic Health Evaluation; CI, confidence interval; CnsKP: carbapenem non-susceptible Klebsiella pneumoniae; OR, odds ratio.