Table 4 Baseline Characteristics of the study Samples.

From: An APOC3 3′UTR variant associated with plasma triglycerides levels and coronary heart disease by creating a functional miR-4271 binding site

Characteristics

The sequencing population

The general population

The CAD population

Controls (n = 400)

Controls (n = 2982)

Cases (n = 2627)

Age, yrs

59.3 ± 10.5

58.5 ± 10.3

60.0 ± 10.5

Men, %

63.0

55.4

55.3

BMI, kg/m2

22.4 ± 2.8

23.2 ± 3.2

21.4 ± 2.5*

SBP, mm Hg

136.8 ± 16.4

138.7 ± 24.4

144.5 ± 21.3*

DBP, mm Hg

81.9 ± 12.7

81.1 ± 12.7

80.4 ± 13.4

Hypertension, %

0

417 (13.98)

1640(62.4)*

Diabetes, %

0

105 (3.52)

450(17.1)*

Hyperlipidemia, %

0

88 (2.95)

357(13.6)*

Smokers, %

0

889 (29.8)

1550(59.0)*

TC (mmol/L)

4.08 ± 0.59

4.31 ± 1.61

4.93 ± 0.97*

HDL (mmol/L)

1.31 ± 0.30

1.46 ± 0.35

2.76 ± 0.79*

LDL (mmol/L)

1.23 ± 0.55

1.12 ± 2.55

2.51 ± 1.03*

TG (mmol/L)

1.05 ± 0.31

1.46 ± 0.99

1.86 ± 1.96*

  1. BMI indicates body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure;
  2. Values are expressed as mean  ±  SD unless otherwise noted;
  3. &test for differences between cases and controls. *p < 0.05. *p < 0.01.
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