Figure 1
From: Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer
Flowchart of the analysis pipeline.
We performed alignment and quantification on each RNA-seq sample, and then performed differential expression (DE) analysis to identify breast cancer-associated lncRNAs and mRNAs, as well as co-expression analysis between lncRNAs and mRNAs to infer potential function of lncRNAs considering two possible underlying mechanisms. Finally, our findings were validated using external TCGA dataset and other available bioinformatics resources including TANRIC functional annotation and pathway analysis.
