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Figure 1

From: Indole-3- carbinol enhances sorafenib cytotoxicity in hepatocellular carcinoma cells: A mechanistic study

Figure 1

Cytotoxicity of I3C, sorafenib and their combination in HepG2 and Huh-7 cells.

(A) Cytotoxicity of various concentrations of I3C in HepG2 and Huh-7 cell lines. Data are means ± SD of 3 independent experiments. ap < 0.05: statistically significant when compared to the control value using ANOVA followed by Dunnett test as post-hoc test. (B) Cytotoxicity of various concentrations of sorafenib alone or in combination with I3C in HepG2 and Huh-7 cell lines. Data are means ± SD of 3 independent experiments. ap < 0.05: statistically significant when compared to the control value using ANOVA followed by Dunnett test as post-hoc test. bp < 0.05: statistically significant when compared to the corresponding group treated with sorafenib alone using unpaired t-test.

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