Table 1 The parameters of the different dietary groups.

From: A low-salt diet increases the expression of renal sirtuin 1 through activation of the ghrelin receptor in rats

 

Control

LoS

HiS

CR

P value

Baseline bwt (g)

184 ± 8

187 ± 14

190 ± 10

190 ± 9

0.755

7-day bwt (g)

233 ± 28

218 ± 11

230 ± 17

175 ± 9a

1.5 × 10−4

Systolic BP (mmHg)

107.3 ± 1.8

108.0 ± 1.7

106.7 ± 2.9

104.3 ± 1.4

0.623

Food intake (g/day)

22.2 ± 6.8

20.4 ± 3.8

14.0 ± 4.3b

11.3 ± 1.0c

2.2 × 10−22

Water intake (mL/day)

36.1 ± 9.9

30.0 ± 14.1

98.3 ± 26.9d

26.8 ± 7.9

6.5 × 10−48

Urine output (mL/day)

16.9 ± 5.6

21.5 ± 13.9

81.2 ± 17.3e

20.1 ± 6.9

5.9 × 10−55

Plasma sodium (mM)

136.5 ± 3.5

137.5 ± 3.4

138.8 ± 2.8

145.7 ± 6.4

0.089

Plasma creatinine (mg/dL)

0.45 ± 0.04

0.44 ± 0.02

0.48 ± 0.03

0.40 ± 0.03

0.832

Plasma aldosterone (ng/dL)

31.0 ± 17.7

29.2 ± 10.4

34.5 ± 22.0

25.3 ± 8.0

0.893

FENa (%)

1.12 ± 0.86

<0.1

8.71 ± 5.32

1.00 ± 0.45

NA

  1. The parameters were compared among the groups by one-way analyses of variance with Bonferroni post hoc tests. aP < 0.005 vs. the other three groups; bP < 1 × 10−7 vs. the control and LoS groups, but P = 0.07 vs. the CR group; cP < 1 × 10−7 vs. the control and LoS groups, but P = 0.07 vs. the HiS group; dP < 1 × 10−35 vs. the other three groups; eP < 1 × 10−37 vs. the other three groups; Bwt: body weight, BP: blood pressure, LoS: low-salt diet, HiS: high-salt diet, CR: calorie restriction, FENa: fraction excretion of sodium, NA: not available. N = 6 in each group.