Figure 5

Noise amplification (SA) and noise susceptibility (SS) curves for variable E2F as parameters ΓE and ΓM vary.
5 different values of parameter ΓM (legend bar) were used and the values of the other parameters are given in Table 1. (a) Noise susceptibility at the on state. (b) Noise amplification at the on state. (c) Noise susceptibility at the off state. (d) Noise amplification at the off state. Initial conditions that lead to the on and off states were chosen, and the model values at the steady states were used in calculating noise amplification and susceptibility (Methods). Results using different pairs of parameters are given in Supplementary Figs 2–6.