Table 2 Summary of significant differences between timepoints (Time) within each oxygen treatment (O2).

From: Cold tolerance is unaffected by oxygen availability despite changes in anaerobic metabolism

Group1

O2

0

0

0

2.5

2.5

2.5

5

5

5

10

10

10

21

21

21

40

40

40

vs

Time

1

1

2

1

1

2

1

1

2

1

1

2

1

1

2

1

1

2

Group 2

O2

0

0

0

2.5

2.5

2.5

5

5

5

10

10

10

21

21

21

40

40

40

 

Time

2

3

3

2

3

3

2

3

3

2

3

3

2

3

3

2

3

3

Amino acids and peptides

 Ala

    

 

*

 

*

      

 

 Arg

       

         

 

 Asn

  

*

*

 

 

*

       

 

 Asp

       

*

          

 3-Ala

     

*

 

          

 Cys

  

     

*

        

 

 Glu

       

      

*

*

 

 Gln

 

*

   

        

  

 Gly

       

*

          

 His

                   

 Ile

 

 

  

          

 Leu

 

 

*

  

*

        

 

 Lys

  

 

*

*

             

 Met

        

          

 Orn

     

*

            

 Phe

     

*

  

*

        

*

 

 Pro

            

    

 Ser

   

*

   

*

*

   

*

     

 Thr

                   

 Trp

    

  

          

 Tyr

                   

 Val

    

*

 

*

        

 

 2-Aminobutyric acid (2-Aba)

       

           

 Cystathionine (CTH)

                   

 3,4-Dihydroxyphenylalanine (DOPA)

 

*

 

*

             

 Glutathione (GSH)

    

*

             

TCA cycle metabolites

 Aconitic acid

    

*

             

 2-Ketoglutaric acid (2-KG)

                   

 Citric acid

    

*

 

           

 Fumaric acid

    

*

 

*

   

*

*

       

 Malic acid

  

*

*

 

*

 

*

         

 Pyruvic acid

          

       

 Succinic acid

    

            

 

Other organic acids

 Adipic acid

                   

 Lactic acid

 

*

 

*

 

       

    

 Maleic acid

    

*

 

*

   

*

*

       

 Linoleic acid

                 

*

 

 Linolenic acid

        

        

 

 Margaric acid

                   

 Oleic acid

                 

 

 Palmitic acid

                 

*

 

 Stearic acid

                 

*

 

Biogenic amine

 Putrescine

       

    

      
  1. Time 1 is before chill coma, time 2 is during chill coma and time 3 is after chill coma. Significant effects (P < 0.0037 after false discovery rate correction using the Benjamini-Hochberg procedure75) are indicated by symbols. The level of significance is indicated by the symbols: blank is P > 0.0037, dot (•) is 0.0037>P > 0.001, and star (*) is P < 0.001.