Table 1 Characteristics of subjects in model group and validation group.

From: Diagnostic accuracy and clinical utility of a new noninvasive index for hepatic steatosis in patients with hepatitis B virus infection

Parameters

Model group (n = 182)

Validation group (n = 182)

Test value

P value

Male (n,%)

148 (81.3)

150 (82.4)

0.07

0.786#

Age (years)

33.8 ± 9.1

35.0 ± 9.9

−1.246

0.213

BMI (kg/m2)

23.3 ± 4.2

22.6 ± 3.4

1.793

0.074

WC (cm)

72.7 ± 12.5

69.4 ± 11.6

2.616

0.009

ALT (U/L)

73 (39, 150)

71 (39, 159)

0.524

0.946*

AST (U/L)

50 (34, 84)

51 (36, 80)

0.472

0.979*

γ-GT (U/L)

55 (30, 115)

54 (30, 107)

0.891

0.405*

Log DNA (copies/ml)

4.7 ± 2.8

4.6 ± 2.8

0.277

0.782

Albumin (G/L)

43.8 ± 4.7

44.7 ± 4.5

−1.702

0.09

WBC (109/l)

5.7 ± 1.6

5.7 ± 1.4

0.136

0.892

HGB (G/L)

145.0 ± 16.0

144.0 ± 15.7

0.475

0.635

PLT (109/l)

183.9 ± 55.1

184.7 ± 53.8

−0.145

0.885

PT (second)

12.4 ± 1.3

12.4 ± 1.3

−0.322

0.748

SUA (mmol/l)

350.5 ± 93.2

351.7 ± 100.8

−0.119

0.906

FPG (mmol/l)

4.8 ± 0.9

4.8 ± 1.1

−0.091

0.923

TC (mmol/l)

4.5 ± 1.0

4.4 ± 1.0

0.576

0.565

TG (mmol/l)

1.3 ± 0.9

1.3 ± 0.8

−0.118

0.906

HDL (mmol/l)

1.4 ± 0.4

1.3 ± 0.4

1.922

0.055

LDL (mmol/l)

2.4 ± 0.7

2.4 ± 0.8

−0.233

0.816

Inflammation Grade 1 (n,%)

8 (4.4)

10 (5.5)

2.18

0.535*

Inflammation Grade 2 (n,%)

80 (44.0)

92 (50.5)

  

Inflammation Grade 3 (n,%)

69 (37.9)

59 (32.4)

  

Inflammation Grade 4 (n,%)

25 (13.7)

21 (11.5)

  

Fibrosis Stage 1 (n,%)

27 (14.8)

28 (15.4)

2.95

0.399*

Fibrosis Stage 2 (n,%)

72 (39.6)

69 (37.9)

  

Fibrosis Stage 3 (n,%)

40 (22.0)

52 (28.6)

  

Fibrosis Stage 4 (n,%)

43 (23.6)

33 (18.1)

  

Steatosis grade0 (n,%)

123 (67.6)

123 (67.6)

0.56

0.906*

Steatosis grade1 (n,%)

44 (24.2)

47 (25.8)

  

Steatosis grade2 (n,%)

9 (4.9)

8 (4.4)

  

Steatosis grade3 (n,%)

6 (3.3)

4 (2.2)

  

Fatty liver diagnosed by US (n,%)

30 (16.5)

34 (18.7)

0.3

0.582#

Antiviral therapy (n,%)

40 (22.0)

32 (17.6)

1.11

0.293#

HBeAg positive (n,%)

124 (68.1)

114 (62.6)

1.21

0.271#

HBV DNA positive (n,%)

143 (78.6)

141 (77.5)

0.06

0.80#

  1. *Kruskal-Wallis H test.
  2. #Chi-square test. Hepatic steatosis were diagnosed by liver biopsy.
  3. SUA, Serum uric acid; FPG, Fasting plasma glucose; TC, Total cholesterol; TG, Triglyceride; HDL, high-density lipoprotein cholestero; LDL, low-density lipoprotein cholestero; ALT, Alanine aminotransferase; AST, Aspartate aminotransferase; γ-GT, γ-glutamyl transferase; BMI, body mass index; WC, waist circumference; WBC, white blood cell; PLT, blood platelet; HGB, hemoglobin; PT, Prothrombin time.Continuous data were expressed as mean ± SD or median (uartile range) depending on the normality of the data. Categorical variables were expressed as proportions.
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