Table 2 Top Ten-Ranking GeneGo Pathway Maps and GeneGo Process Networks Associated with the Differential Proteins Based on MetaCore Database Analysis.

From: The Extrinsic Coagulation Pathway: a Biomarker for Suicidal Behavior in Major Depressive Disorder

Ā 

P-value

GeneGo Pathway Maps

1. Blood coagulation

1.444 × 10āˆ’13

2. Immune response: classical complement pathway

4.388 × 10āˆ’7

3. Immune response: alternative complement pathway

2.215 × 10āˆ’4

4. Immune response: lectin-induced complement pathway

4.376 × 10āˆ’4

5. Immune response: sialic-acid receptors (Siglecs) signaling

3.643 × 10āˆ’2

6. Ascorbate metabolism

5.417 × 10āˆ’2

7. Development: thrombopoetin signaling via JAK-STAT pathway

6.582 × 10āˆ’2

8. Glycolysis and gluconeogenesis p.3/Human version

7.159 × 10āˆ’2

9. Glycolysis and gluconeogenesis p.3

7.159 × 10āˆ’2

10. Development: leptin signaling via JAK/STAT and MAPK cascades

7.446 × 10āˆ’2

GeneGo Process Networks

1. Blood coagulation

9.927 × 10āˆ’11

2. Inflammation: kallikrein-kinin system

3.569 × 10āˆ’10

3. Inflammation: complement system

1.759 × 10āˆ’7

4. Inflammation: IL-6 signaling

3.438 × 10āˆ’7

5. Signal transduction: leptin signaling

3.322 × 10āˆ’3

6. Cell adhesion: platelet-endothelium-leucocyte interactions

3.399 × 10āˆ’3

7. Development: ossification and bone remodeling

1.313 × 10āˆ’2

8. Proteolysis: ECM remodeling

1.336 × 10āˆ’2

9. Inflammation: protein C signaling

2.517 × 10āˆ’2

10. Development: angiogenesis regulation

4.098 × 10āˆ’2