Figure 1
From: 24-hour-restraint stress induces long-term depressive-like phenotypes in mice
The 24-hour-restraint stress induced depressive-like behaviors.
(A) Experiment designs to test the short-term (S group) and long-term (L group) impact of the restraint on mice. (B–C) Sucrose preference percentage of 24 hours in sucrose preference test of S group (B) and L group (C). The p-value (t-test) for S group is <0.05 (N = 24 vs. 25) and L group is <0.05 (N = 23 vs. 25). (D–E) The struggling time before the first abandon and total time of immobility in the forced swimming test of S group (D) and L group (E). The p-values of t-test of first abandon are <0.05 (N = 24 vs. N = 25) and <0.01(N = 25 vs. 28) respectively. And the p-values of t-test of immobility are <0.01 (N = 24 vs. N = 25) and <0.01 (N = 26 vs. 28) respectively. (F,G) The percentage of freezing time in the contextual fear conditioning test for the S group (F) and L group (G). The p-values of t-test are 0.30 (N = 21 vs. 23) and <0.001 (N = 20 vs. 21) respectively. Data are presented as mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001.
