Figure 2
From: 24-hour-restraint stress induces long-term depressive-like phenotypes in mice
Alternations of glucose metabolism by small animal PET scanning.
Glucose uptake is measured as %ID/cc (%injected dose per mL of tissue). (A) Experiment design of the PET scanning. (B) The average glucose uptake of the whole brain of S group shows no difference between control and restraint mice (N = 7 vs. 9). (C) The changes of glucose uptake in brain regions of S group. Glucose uptake of brain regions including STR, CTX, BFS, LAMY, SC, OLF, RIC is significantly increased in restraint mice. (D) The average glucose uptake of the whole brain for L group is significantly decreased in restraint mice (N = 8 vs. N = 7), p value of student t-test is<0.01. (E) The glucose uptake of different brain regions of L group. Brain regions such as STR, CTX, HIP, THA, CG, SC, MID and IC were significantly decreased in restraint mice. (F) Representatives of the glucose uptake of S and L group. Data are presented as mean ± SEM, *P < 0.05, **P < 0.01. Abbreviations: RSTR, right striatum; LSTR, left striatum; CTX, cortex; RHIP, right hippocampal region; LHIP, left hippocampal region; THA, thalamus; CB, cerebellum; BFS, basal forebrain/septum; HYP, hypothalamus; RAMY, right amygdala; LAMY, left amygdala; CG, cingulate gyrus; SC, superior colliculus; OLF, olfactory areas; RMID, right midbrain; LMID, left midbrain; LIC, left inferior colliculus; RIC, right inferior colliculus.
