Figure 4
From: 24-hour-restraint stress induces long-term depressive-like phenotypes in mice
High-throughput gene expression analysis in short-term (S) and long-term (L) brain tissues (PFC and hippocampus) by microarrays.
(A) Number of detected differentially expressed genes (DEGs). (B) Number of overlapping DEGs among short-term PFC, long-term PFC, short-term hippocampus and long-term hippocampus. (C) Enriched KEGG pathways revealed by the DEGs. Enrichments from up-regulated DEGs and down-regulated DEGs are shown in “red” and “green” respectively. (D–E). Fold changes of selected genes in PFC (D) and hippocampus (E) of S group measured by quantitative RT-PCR. F-G. Fold changes of selected genes in PFC (F) and hippocampus (G) of L group. Data are presented as mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001.
