Figure 4
Connectivity pairs with significant differences and clinical correlations at the connectivity level.
(A) Topological mapping of 50 intranetwork and internetwork connectivity pairs with significant differences among the HC, DMCN and DMCI groups (ANOVA, permutation corrected P < 0.05); node with different color means different subnetwork, grey edge means internetwork connectivity, other edges mean intranetwork connectivity. (B–D) Topological mapping of the connectivity pairs with significant differences between HC and DMCN, HC and DMCI, DMCN and DMCI; red edges mean that the connectivity strength of the former group is higher than the latter, blue edges mean converse. (E) Four negative and 2 positive correlations between the connectivity strength and MMSE scores in the DMCI group, (F) 2 negative correlations between the connectivity strength and HbA1c in the DMCI group, (G) 2 negative and 1 positive correlations between the connectivity strength and illness duration in the DMCI group, (H) 1 negative and 2 positive correlations between the connectivity strength and MMSE scores in the DMCN group, (I) 3 negative correlations between the connectivity strength and HbA1c level in the DMCN group; red line represents positive correlation, blue line represents negative correlation.
