Figure 3

Comparison of the simulated fluxes at ambient CO2 based on the measured and randomly generated gene expression of specific enzymes for Synechocystis 6803 (A) and Synechococcus 7942 (B). Black represents a simulation of fluxes at AC based on the measured changes in gene expression after a shift from HC to AC. Grey indicates the mean of the simulated fluxes at AC based on 20 independent runs of randomly redistributed changes of measured gene expression, applied as weight factors for AC instead of measured changes. The error bars represent standard deviation. For better illustration, fluxes through PGM, PKET and the G6P sink are increased by factors of 10, 10 and 100, respectively. FBPase–shows the difference of fluxes between FBPase and PFK. Names of enzymes: RuBisCO– ribulose-1,5-bisphosphate carboxylase oxygenase, GAP–glyceraldehyde 3-phosphate dehydrogenase, TPI–triose-phosphate isomerase, SBPase– sedoheptulose-1,7-bisphosphate aldolase, FBPase–fructose-1,6 bisphosphatase, PFK–phosphofructokinase, PPE –phosphopentose epimerase, PGM–phosphoglycerate mutase, PKET–phosphoketolase, G6P sink–synthesis of carbohydrates.