Figure 5
From: Statins affect ETS1-overexpressing triple-negative breast cancer cells by restoring DUSP4 deficiency

Apoptosis assay.
MDA-MB-231 (A) and HCC1806 (B) cells were transfected with control siRNA or DUSP4-targeting siRNA. At 24 h post-transfection, simvastatin was added and cells were incubated an additional 48 h. The distribution of annexin V-FITC/PI staining is shown. Data are expressed as averages for each time point and were calculated using the results from three independent experiments.